PLASMA PROTEIN LABELED WITH LYSINE-ϵ-C14
نویسندگان
چکیده
منابع مشابه
Plasma Protein Labeled with Lysine-ε-c14
The metabolism of homologous plasma proteins, labeled with lysine-epsilon-C(14), after oral administration to dogs has been investigated. The speed of the various processes involved is indicated by the maximum rate of C(14) O(2) excretion which is attained within 1 to 4 hours, the prompt appearance of protein activity in the plasma and disappearance of non-protein activity from it, both virtual...
متن کاملPlasma and Tissue Proteins Produced by Non-hepatic Rat Organs as Studied with Lysine-ε-c14
The non-hepatic tissues in a perfused "carcass" (caudal half of the rat) maintain some physiological functions for as long as 5 to 6 hours of perfusion, including good clearance of lysine-epsilon-C(14) and glucose from the perfusate, and synthesis of both tissue and plasma proteins. The perfused "carcass" tissues incorporate only small amounts of lysine-epsilon-C(14) into the plasma proteins to...
متن کاملIncorporation of C14-labeled substrates into violacein.
Previous studies on the physiological aspects of violacein biosynthesis (DeMoss and Evans, 1959) suggested that only L-tryptophan would serve as the primary source of carbon for pigment formation by Chromobacterium violaceum. In view of the pigment structure suggested by Ballantine et al. (1958), 5-[3-(5-hydroxyindolyl)]-3-(3-isatinyl)-2-pyrrolone, it seemed advisable to determine the actual so...
متن کاملPlasma protein binding of triamcinolone-H3 and hydrocortisone-4-C14.
It has become increasingly apparent in recent years that certain structural alterations of corticosteroids cause an increased biological potency of the resultant steroid (2). A number of chemical and microbiological alteration products of hydrocortisone exhibit enhanced anti-inflammatory potency coupled with unchanged or depressed mineralocorticoid activity (2, 3). As a result, steroids bearing...
متن کاملHemoglobin Labeled by Radioactive Lysine
A dog, doubly depleted of blood cells and plasma proteins, was fed dl-lysine labeled with C(14) in the epsilon carbon position. In the first 8 hours 28 per cent of the administered C(14) was excreted in the urine; in the first 72 hours, 35 per cent. Twenty-four hours after feeding, 4.2 per cent of the fed C(14) was circulating in the plasma, decreasing to 1 per cent at the end of 17 days. The C...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1952
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.96.3.247